Which agent is commonly used to treat Diphyllobothrium latum infections?

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Multiple Choice

Which agent is commonly used to treat Diphyllobothrium latum infections?

Explanation:
Diphyllobothrium latum infections are treated with praziquantel because it is highly effective against cestodes and works by increasing the parasite’s cell membrane permeability to calcium. This causes rapid muscular contraction and paralysis, leading to detachment from the intestinal wall and eventual clearance from the host. The typical regimen is 25 mg/kg taken orally three times a day for one day (total around 75 mg/kg). While niclosamide can be used as an alternative in some cases, praziquantel is preferred due to its broad efficacy and favorable tolerability.

Diphyllobothrium latum infections are treated with praziquantel because it is highly effective against cestodes and works by increasing the parasite’s cell membrane permeability to calcium. This causes rapid muscular contraction and paralysis, leading to detachment from the intestinal wall and eventual clearance from the host. The typical regimen is 25 mg/kg taken orally three times a day for one day (total around 75 mg/kg). While niclosamide can be used as an alternative in some cases, praziquantel is preferred due to its broad efficacy and favorable tolerability.

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