Which agent is used for the treatment of cestodes such as Taenia and Hymenolepis?

• A. Praziquantel
• B. Albendazole
• C. Metronidazole
• D. Nitazoxanide

Answer: (A)

For cestode infections such as Taenia species and Hymenolepis, praziquantel is the drug of choice. It works by increasing calcium permeability in the parasite’s cell membranes, causing rapid, strong muscle contractions and paralysis, and it damages the parasite’s outer tegument. This combination disrupts the worm’s integrity and function, letting the host immune system clear the parasite effectively. The result is high cure rates often achieved with a single dose. While other drugs like albendazole can be used in some situations, praziquantel has the most reliable efficacy against tapeworms and is preferred for treating taeniasis and hymenolepiasis; metronidazole and nitazoxanide target other organisms and are not first-line for cestodes.